Low-density lipoprotein concentration in the normal left coronary artery tree

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Low-density lipoprotein concentration in the normal left coronary artery tree

BACKGROUND The blood flow and transportation of molecules in the cardiovascular system plays a crucial role in the genesis and progression of atherosclerosis. This computational study elucidates the Low Density Lipoprotein (LDL) site concentration in the entire normal human 3D tree of the LCA. METHODS A 3D geometry model of the normal human LCA tree is constructed. Angiographic data used for ...

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Wall shear stress in normal left coronary artery tree.

Despite the fact that the role of wall shear stress (WSS) as a local mechanical factor in atherogenesis is well established, its distribution over the entire normal human left coronary artery (LCA) tree has not yet been studied. A three-dimensional computer generated model of the epicardial LCA tree, based on averaged human data set extracted from angiographies, was adopted for finite-element a...

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ژورنال

عنوان ژورنال: BioMedical Engineering OnLine

سال: 2008

ISSN: 1475-925X

DOI: 10.1186/1475-925x-7-26